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Sunday, May 30, 2010

Lactose Intolerance Q1 : I try to answer

yeszzaa..yesterday someone asked me ‘’so doc, kalau ada lactose yang xdipecahkan, kenapa mesti diarrhea? =) apa patophysiologynye?’’

About some my explaination last posted maybe not too clear caused its too simple..okey,maybe we can disscuss again now..

Okey,we try to gve some intro about chemistry moment

(this won’t take long) :

Lactose is a two- molecule sugar (or disaccharide) made up of one molecule of glucose and one molecule of galactose.okey, In order to absorb lactose our body needs to break the bond between the two simple sugars using the enzyme lactase.

Lactase is actually abundant in the human intestine in infancy, but its level akan berkurang apabila umur semakin meningkat.Another important of this lactase enzyme yang saya terjumpa kt 1 medical site is ( Lactase production will help our body’s ability to turn genes on and off; while the genetic code for producing lactase is in the cell, the cell can turn off production partially or completely.)

Those of us with lower levels of lactase don’t break up some or all of the dietary lactose, which will reach the large intestine undigested; there, bacteria will happily feast on the sugar and produce gasses.Contohnya carbon dioxide, hydrogen and methane. Kemudian,those undigested sugars akan ambil or draw water from our intestinal walls, causing bloating and diarrhea.

But, don’t think those people yg kurang lactase bermaksud lactose intolerance,most people yang low lactase juga xda these signs or symptoms (the common ones being diarrhea, abdominal pain, gas, bloating or nausea).
Only people yang ada low-lactase levels (setelah di diagnos oleh doctor) and menghidap signs and symptoms ini akan diisytiharkan sebagai, lactose intolerance.

p/,Doc Fadhli,do you think its clear?(✿◠‿◠)


  1. hoho..good to diagnos this patient? whatinvestigation we need to do? and how to manage this patient?

  2. i would like to answer your Q after my biochem finished this tuesday..thats my pleasure...hihi

  3. hoho...hebat eh kow,memanfaatkn blog..nice....


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